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Trimetazidine vastarel This leads to an exacerbation of ischemic injury and decreased cardiac efficiency during reperfusion. Trimetazidine is an anti-ischemic anti-anginal metabolic agent, which improves myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity, which results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation.

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Trimetazidine is well established in stable coronary artery diseasePreliminary evidence suggests trimetazidine vastarel trimetazidine might be an effective drug in diabetic and non-diabetic patients with chronic heart failure and in those trimetazidine vastarel peripheral artery diseaseTrimetazidine has been generally well tolerated in clinical trials but some recently reported adverse drug reactions require careful evaluation in studies with longer follow-up Trimetazidine is a cytoprotective drug that normalizes metabolic disturbances in low-flow ischemia via several not yet fully understood mechanisms of action.

Trimetazidine also increases pyruvate dehydrogenase activity, which starts restoring homeostasis between glucose oxidation and glycolysis, imbalanced during ischaemia1 3. The best known trimetazidine mechanism of action is its capacity trimetazidine vastarel inhibit -oxidation of free trimetazidine vastarel acid FFA FFA oxidation provides more energy, but it is associated with increased oxygen consumption.

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Heart. Chen JD, Zhao LK, Tian F, et al. Evaluation of the myocardial protection of trimetazidine during percutaneous coronary intervention: a multi-center randomized and controlled clinical study.

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TRIMPOL I, a vastarel mr study. Szwed H, Sadowski Z, Elikowski W, et al. Efficacy and tolerance of trimetazidine, a metabolic antianginal, in combination with a hemodynamic vastarel mr in stable exertion angina.

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Danchin N, Marzilli M, Parkhomenko A, et al. Efficacy comparison of trimetazidine with therapeutic alternatives in stable angina pectoris: a network meta-analysis. Cardiology. PMC free article PubMed Google Scholar 24.

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It is not intended as a tab vastarel mr for the expertise and judgement of your physician, pharmacist or other healthcare professional. rimetazidine is reported as an ingredient of Vastarel-MR in the following countries: Trimetazidine dihydrochloride a derivative of Trimetazidine is reported as an ingredient of Vastarel-MR in the following countries: Important Notice: The Drugs.

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All articles by trimetazidine vastarel:

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5 Trimetazidine has been treated as a drug with a high safety and tolerability profile. 6 It interacts with monoamine oxidase inhibitors. In 2014, Chinese Olympic champion swimmer Sun Yang was caught with a urine test and banned by the Chinese Swimming Association for 3 months. ...

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Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy. Tuunanen H, Engblom E, Naum A, et al. ...

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